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202105003.pdf
文章编号： 1672-6987（2021）05-0019-5； DOI： 10.16351/j.1672-6987.2021.05.003
颜博， 陈程， 王政文， 王少娟， 唐林生*(青岛科技大学 化工学院，山东 青岛 266042）
摘要： 以4-羟基-2,2,6,6-四甲基哌啶氮氧自由基（ZJ-701）和醇为原料，铜吡啶配合物为催化剂，30%过氧化氢为氧化剂，通过氧化和O-烷基化合成了几种1-烷氧基-4-羟基-2,2,6,6-四甲基哌啶醇，通过核磁共振谱、红外光谱和质谱表征了其结构。结果表明：醇烷基对目标产物的合成有明显的影响，当碳数为3，且为直链（正丙醇）时，目标产物的产率最高，且易提纯。
关键词： 1-烷氧基-4-羟基-2,2,6,6-四甲基哌啶醇； 4-羟基-2,2,6,6-四甲基哌啶氮氧自由基； 铜吡啶配合物
中图分类号： TQ 253.2文献标志码： A
引用格式： 颜博， 陈程， 王政文， 等. 1-烷氧基-4-羟基-2,2,6,6-四甲基哌啶醇的催化合成［J］. 青岛科技大学学报(自然科学版), 2021, 42(5): 19-23.
YAN Bo， CHEN Cheng， WANG Zhengwen， et al. Catalytic synthesis of 1-alkoxy-4-hydroxyl-2,2,6,6-tetramethylpiperidine［J］. Journal of Qingdao University of Science and Technology（Natural Science Edition), 2021， 42（5）： 19-23.
Catalytic Synthesis of 1-Alkoxy-4-hydroxyl-2,2,6,6-tetramethylpiperidine
YAN Bo， CHEN Cheng， WANG Zhengwen， WANG Shaojuan， TANG Linsheng
(College of Chemical Engineering, Qingdao University of Science and Technology, Qingdao 266042，China)
Abstract: Using 4-hydroxy-2,2,6,6-tetramethyl-piperidinooxy(ZJ-701) and alcohols as raw materials, 30 % H2O2 as oxidant and Cu complex of pyridine as catalyst, several 1-alkoxy-4-hydroxyl-2,2,6,6-tetramethylpiperidines were synthesized by oxidation and O-alkylation, and their structure were characterized by NMR, IR and MS in this paper. The results reveals that the alkyl of alcohol has an obvious effect on the synthesis of the target products, when the carbon number of alkyl is 3, and its chain is linear, the yield of the target products is highest, and the target products is easy to purification. Compared with the mothed reported in literatures, the yield is increased markedly.
Key words: 1-alkoxy-4-hydroxyl-2,2,6,6-tetramethylpiperidine； 4-hydroxy-2,2,6,6-tetramethylpiperidinooxy; Cu complex of pyridine
收稿日期： 2020-11-21
基金项目： 山东省自然科学基金项目（ZR2015BL025）；山东省教委基金项目（J16LC21）.
作者简介： 颜博（1994—），男，硕士研究生.*通信联系人.
