噻二唑和石墨烯导电共聚物修饰电极测定呋喃西林

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文章编号： 16726987（2019）02002406； DOI： 10.16351/j.16726987.2019.02.003

张莉， 辛晨， 赵常志*

(青岛科技大学 化学与分子工程学院，山东 青岛 266042）

摘要： 以5氨基2巯基1,3,4噻二唑和氧化石墨烯为原料，采用电化学共聚的方法制备了噻二唑/石墨烯导电聚合物修饰电极。利用该电极对呋喃西林的选择性响应，实现了对药物和消毒剂中呋喃西林的电化学分析。在优化的实验条件下，导电共聚物修饰电极的差分脉冲电流与002~200 μg·mL-1范围内的呋喃西林浓度呈线性关系，线性相关系数为0997 9，检出限为001 μg·mL-1。对实际样品测定的相对标准偏差小于556（n=5），加标回收率为952%~1030%。

关键词： 5氨基2巯基1,3,4噻二唑； 氧化石墨烯； 呋喃西林； 修饰电极； 电化学共聚

中图分类号： O 462.3；O 657.1文献标志码： A

引用格式：张莉， 辛晨， 赵常志. 噻二唑和石墨烯导电共聚物修饰电极测定呋喃西林\[J\]. 青岛科技大学学报（自然科学版）， 2019， 40（2）： 2429.

ZHANG Li，XIN Chen，ZHAO Changzhi. Determination of nitrofurazone with conductive copolymer modified electrode prepared by thiadiazole and graphene\[J\]. Journal of Qingdao University of Science and Technology（Natural Science Edition), 2019, 40(2)： 2429.

Determination of Nitrofurazone with Conductive Copolymer Modified Electrode Prepared by Thiadiazole and Graphene

ZHANG Li，XIN Chen，ZHAO Changzhi

(College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, China)

Abstract: 5Amino2mercapto1,3,4thiadiazole and graphene oxide were used as raw materials to prepare thiadiazole/grapheneconductive copolymer modified electrode by using electrochemical copolymerization. The selective response of the modified electrode to the nitrofurazone was utilized to realize the electrochemical analysis of nitrofurazone in drug and disinfectant. Under the optimal experimental conditions, the differential pulse current of the conductive copolymer modified electrode showed a linear relationship with concentration of nitrofuzonein in the range of 002—200 μg·mL-1 with a linear correlation coefficient of 0997 9 and a detection limit of 001 μg·mL-1. The relative standard deviations (RSDs) were less than 556 (n=5) and the spiked recoveries ranged from 952% to 103.0% for the determination of the actual samples.

Key words:5amino2mercapto1,3,4thiadiazole; grapheneoxide; nitrofurazone; modified electrode; electrochemical copolymerization

收稿日期： 20180428

基金项目： 国家自然科学基金项目（21475072）.

作者简介： 张莉（1993—），女，硕士研究生.*通信联系人.