PDF全文下载：2017030022
张画轻，杨曦，黄雪松，许良忠*
(青岛科技大学 化学与分子工程学院；农用化学品研究所，山东 青岛266042)
摘要： 将新烟碱类杀虫剂的活性基团2-氯-5-吡啶甲基，引入邻甲酰胺基苯甲酰胺类杀虫剂的结构中，合成了系列氯代吡啶基吡唑酰胺类化合物。通过液质联用、核磁氢谱确定了结构。生物活性测试结果表明：部分目标化合物在5 mg·L-1浓度下对小菜蛾（Plutella xyllostella）致死率达到100%，在100 mg·L-1对桃蚜（Myzus persicae Sulzer）致死率达到85%。
关键词：邻甲酰胺基苯甲酰胺；合成；生物活性
中图分类号：O 622.5文献标志码：A
引用格式：张画轻，杨曦，黄雪松，等.3-（2-氯-5-吡啶甲氧基）-吡唑酰胺类化合物的合成及其生物活性\[J\].青岛科技大学学报（自然科学版），2017，38（3）：22-26.
ZHANG Huaqing,YANG Xi,HUANG Xuesong,et al.Synthesis and biological activity of 3-(2-chloro-5-pyridylmethoxy)-pyrazole amides\[J\].Journal of Qingdao University of Science and Technology（Natural Science Edition),2017,38(3)：22-26.
Synthesis and Biological Activity of 3-(2-Chloro-5-pyridylmethoxy)-pyrazole Amides
ZHANG Huaqing, YANG Xi, HUANG Xuesong, XU Liangzhong
(College of Chemistry and Molecular Engineering;Agricultural Chemicals Research Institute, Qingdao University of Science and Technology, Qingdao 266042, China)
Abstract: A series of chloro-pyridyl pyrazole amides were synthesized by introducing the active group 2-chloro-5-pyridylmethyl of the new neonicotinoid insecticides into the structure of anthranilic diamides. The structures were conformed by LC-MS and 1H NMR. The biological activities were tested. The mortality rate of some compound against Plutella xyllostella was 100% at the concentration of 5 mg·L-1, and at 100 mg·L-1 against Myzus persicae Sulzer reached 85%.
Key words: anthranilic diamides； synthesis； biological activity
收稿日期：2015-11-28
作者简介：张画轻（1990—），男，硕士研究生.*通信联系人.
文章编号：16726987（2017）03002205； DOI： 10.16351/j.1672-6987.2017.03.004
