壳聚糖及其衍生物在创口敷料中的应用研究新进展

PDF全文下载：2016060591

张永勤，田敏，张捷，钟倩，吴旭东，沈悦聪，胡佳倩

（青岛科技大学化工学院，山东青岛266042）

摘要：壳聚糖及其衍生物因具有抗菌、透气、生物相容、生物粘附等特点已广泛应用于创口敷料的研制中。市售创口敷料有很多，然而并非都满足理想的创口愈合过程的要求，如广谱抗菌性、吸水性、溶胀性、机械强度等。本文综述了近年来为改进壳聚糖基创口敷料性能的研究新进展，并对其进一步的研究方向进行了展望。

关键词：壳聚糖;创口;敷料;  创口愈合;研究进展

中图分类号：O 636.1文献标志码：A

Recent Advances of Chitosan Derivatives and Their Application in Wound Dressing

 ZHANG Yongqin, TIAN Min, ZHANG Jie, ZHONG Qian, WU Xudong， SHEN Yuecong, HU Jiaqian

(College of Chemical Engineering, Qingdao University of Science and Technology,Qingdao 266042,China)

Abstract: Wound dressing is one of the most promising medical applications for chitosan and its derivatives owing to their advantages as antimicrobial character, gas permeability, biocompatibility, bioadhesion, etc. A variety of wound dressings are available, However, not all of the wound dressings  meet the specific requirements of an ideal wound dressing to consider every aspect within the wound healing cascade. For example, widespectrum antimicrobial properties, wateruptake, swelling, machinery performance, etc.  This review aims at taking  a closer look on the chitosan and its derivatives and their applications in wound dressings, and to prospect the future research on wound dressing materials.

Key words: chitosan; wound；dressing; wound  healing; research advances

收稿日期：2016-09-22

基金项目：山东省自然科学基金项目（ZR2013CM027）.

作者简介：张永勤（1965—），女，教授.

文章编号：16726987（2016）06059108；DOI：10.16351/j.16726987.2016.06.001