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202104005.pdf
文章编号： 1672-6987（2021）04-0034-05； DOI： 10.16351/j.1672-6987.2021.04.005
程绚莺, 陈佃昆, 谢传欣*(青岛科技大学 环境与安全工程学院，山东 青岛 266042）
摘要： 介绍一种由6-羟基己酸制备ε-己内酯的方法,该方法是将6-羟基己酸经过甲醇酯化得到6-羟基己酸甲酯、然后以γ-Al2O3为催化剂,6-羟基己酸甲酯经过环化转化成ε-己内酯,并研究了醇酸比、催化剂用量、温度对酯化率的影响,考察了环合温度对己内酯选择性的影响。最终确定：6-羟基己酸在醇酸比(质量比)为3、温度为55 ℃、催化剂用量为2.5%（相对于6-羟基己酸的质量而言）,环合温度为320 ℃的条件下ε-己内酯选择性高达75.6%。
关键词： 6-羟基己酸； 酯化； 环化； ε-己内酯
中图分类号： TQ 032.4文献标志码： A
引用格式： 程绚莺, 陈佃昆, 谢传欣. 6-羟基己酸甲酯合成ε-己内酯［J］. 青岛科技大学学报(自然科学版), 2021, 42(4): 34-38.
CHENG Xuanying, CHEN Diankun, XIE Chuanxin. Preparation of ε-caprolactone from 6-hydroxycaproic［J］. Journal of Qingdao University of Science and Technology（Natural Science Edition), 2021， 42（4）： 34-38.
Preparation of ε-Caprolactone from 6-Hydroxycaproic
CHENG Xuanying, CHEN Diankun, XIE Chuanxin
(College of Environment and Safety Engineering, Qingdao University of Science and Technology， Qingdao 266042， China)
Abstract: A method for preparing ε-caprolactone from 6-hydroxycaproic acid is to esterify 6-hydroxycaproic acid with methanol to obtain methyl 6-hydroxycaproic acid, and then cyclize the methyl 6-hydroxycaproic acid into ε-caprolactone with γ-Al2O3 as catalyst. Finally, it was determined that the selectivity of ε-caprolactone was as high as 75.6% under the conditions of alcohol-acid ratio of 3, temperature of 50 ℃, catalyst dosage of 2.5% (relative to the mass of 6-hydroxycaproic acid) and cyclization temperature of 320 ℃.
Key words: 6-hydroxycaproic acid； esterification； cyclization； ε-caprolactone
收稿日期： 2020-11-03
基金项目： 国家重点研发计划项目（2017YFC0804801）.
作者简介： 程绚莺(1997—),女,硕士研究生.*通信联系人.
