全文下载：2012060560
冯柏成， 李同全， 张庆云
（青岛科技大学 化工学院， 山东 青岛 266042）
摘要： 以苯硫酚钠和对硝基氯苯为原料，经过取代、还原、重氮化、水解4步反应，最终合成了4-苯硫基苯酚，通过单因素实验确定了还原反应的较佳条件是：原料配比n（4-硝基二苯硫醚）∶n（水合肼）=1∶2.5，催化剂三氯化铁用量为4-硝基二苯硫醚质量的3.0%，反应温度70 ℃，反应时间4.5 h。目标产物4-苯硫基苯酚总收率约为64%，纯度为95%。目标产物的结构通过IR、GC-MS和1H NMR进行了确证。
关键词： 4-苯硫基苯酚； 对硝基氯苯； 重氮化
中图分类号： TQ 247.2文献标志码： A
Preparation and Characterization of 4-Thiophenylphenol
FENG Bai-cheng, LI Tong-quan, ZHANG Qing-yun
（College of Chemical Engineering, Qingdao University of Science and Technology, Qingdao 266042,China）
Abstract: 4-Thiophenylphenol was synthesized using sodium thiophenoxide and 4-nitrochlorobenzene as raw materials by nucleophilic substitution, reduction, diazotization, and hydrolysis. The reduction conditions were optimized and the obtained optimum conditions were n(4-nitrodiphenyl sulfide)∶n(hydrazine hydrate)=1∶2.5, catalyst dosage 3% (based on the weight of 4-nitrodiphenyl sulfide), reaction temperature 70 ℃ and time 4.5 h. The yield of 4-thiophenylphenol was about 64% with the purity of 95%. The structure of the target compound was determined by IR, MS and 1H NMR.
Key words: 4-thiophenylphenol; 4-nitrochlorobenzene; diazotization
收稿日期：2012-01-05
作者简介：冯柏成（1965—），男，副教授.
