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N-取代苯基马来酰亚胺的合成及抗菌、缓蚀活性研究

作者:时间:2014-11-21点击数:

PDF全文下载:2011010030

杨丰科,  姜萍

 (青岛科技大学 化工学院,山东 青岛 266042)

 摘要:以顺丁烯二酸酐和苯胺为原料,在醋酸钴、乙酸酐、三乙胺催化下,合成了17种N-取代苯基马来酰亚胺,并对化合物的抑菌及缓蚀活性进行了初步探讨。结果表明:该类化合物对革兰氏阳性菌和革兰氏阴性菌均有较好的抑制效果,部分化合物对铜还表现出缓蚀活性。

关键词: N-取代苯基马来酰亚胺; 抑菌活性;  缓蚀活性

 中图分类号:  O 621.3                          文献标志码:  A

 Synthesis, Antimicrobial and Corrosion-inhibiting Activities of N-Substituted Phenyl Maleimide

 YANG Feng-ke, JIANG Ping

 (College of Chemical Engineering, Qingdao University of Science and Technology, Qingdao 266042,China)

 Abstract: Seventeen N-substituted phenyl maleimide derivatives were synthesized using aniline and maleic anhydride as starting materials, and cobalt acetate, acetic anhydride and triethylamine as catalysts. The antimicrobial and corrosion-inhibiting activities of the obtained products were investigated. The results showed that these compounds exhibited good inhibition effect against Gram-positive bacteria and Gram-negative bacteria, some of the products could decrease the corrosion of copper.

Key words: N-substituted phenyl maleimide;  antimicrobial activity;   corrosion-inhibiting activity

 收稿日期:2010-06-19

基金项目: 山东省自然科学基金项目(ZR2010HM023).

作者简介: 杨丰科(1962—),男,教授.

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